LifeTec Group BioLiver Platform
Thorough testing

Medicine affects your body. That’s a good thing, that’s how it makes you feel better or even cures you, but most of the time the intended purpose is not the only effect:

there are also undesired side-effects that can affect vital organs, sometimes even damage them. 

That’s why it’s crucial to do thorough testing before administering anything to human subjects.

"a platform to keep a liver alive and functional outside of a body"

LifeTec Group continues to develop a platform to keep a liver alive and functional outside of a body. From the animals that are used in food production, not all tissues are actually processed into food. Those tissues that are not intended for human consumption, such as the livers applied in our platform, can be used in life science research and thereby get a meaningful purpose.

In that context, LifeTec Group develops ex-vivo models in which organs are cultured to study interventions and tissue responses as an alternative to animal tests.

  • LifeTec Group - BioLiver Platform
    LifeTec Group - BioLiver Platform
    LifeTec Group - BioLiver Platform
  • LifeTec Group - BioLiver Platform
    LifeTec Group - BioLiver Platform
    LifeTec Group - BioLiver Platform

"compare results"

Testing the response of liver tissue to pharmaceuticals is one application LifeTec Group wants to investigate. For this, there is a need to compare results in the isolated liver with tissue responses in whole animals.

Through the Boost4Health network, we initiated a collaboration with Biotest Facility in Denmark, a partner that is involved in animal studies and would be interested to switch to ex-vivo studies in the future to limit the number of animal experiments needed.

We are exploring the effect that paracetamol, as a well-known drug, has on the liver tissue and if the tissue responses on the isolated liver can be validated against animal data.

Once the model and its response are validated, this would open a lot of possibilities for future pharmacological response studies on isolated organs!

Please do not hesitate to contact Melanie Krüger if you require any further information:

Biochemical Engineer
Melanie Krüger
Call at +31 40 298 93 93 or e-mail us

Relevant links and background information:

This project is part of the Boost4Health community.

Colofon
Boost4Health

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