Every year in April, scientific and medical experts from a broad range of fields including hepatology, gastroenterology, internal medicine, cell biology, transplant surgery, infectious diseases, microbiology and virology, pharmacology, pathology and radiology and imaging come together from around the world to learn about the latest developments in liver research.

‘Close to real’ Research and Training Platforms

With its ‘close to real’ research platforms, its wealth of experience, and its crew of ‘skilled scientific craftsmen’, LifeTec Group contributes significantly to research as well as education. 

You will find one of our ‘craftsmen’, her name is Melanie Krüger, at the International Liver Congress in Vienna between 10 and 14 April:

Meet us in Vienna @ The International Liver Congress
"WE DO NOT HAVE TO KILL ANY ANIMALS"

Melanie started her career with LifeTec Group a few years ago as an ‘early stage researcher’ allocated to the Biogel* project. 

She helped develop the BioLiver platform and is pursuing her PhD within the liver group of Dr. Bart Spee**, at the Veterinary Medicine faculty of University Utrecht.  

"In the BioLiver platform, we can acutely keep a pig liver alive and metabolically active. Because we do this by perfusing livers from the slaughterhouse, we do not have to kill any animals for the experiments" Melanie explained.

Meet us in Vienna @ The International Liver Congress

The BioLiver platform has already proven useful in for example studying the effects of an ablation device from a large electronics manufacturer and the delivery of a chemotherapy.

"We aim to apply it to test many more medical devices and interventions in this relevant environment. Because we achieve physiological blood perfusion and even produce bile, there is no limit in the amount of experiments and tests we can perform. It's a functional liver and many more studies are possible. We even developed a disease model, where we produced a 'fatty liver' in order to be able to study the underlying mechanisms and test potential drug therapies."

"the effect of drugs on our model in comparison to the effect within animals"

"We are now further looking into the effect of drugs on our model in comparison to the effect within animals. With the visit at ILC we want to learn a lot more about the trends and needs in the field of liver diseases and therapies, what is being researched and developed and how we can tailor our platform to best serve the researchers and companies to obtain valuable results without the need for animal experiments."

If you’d like to know more about the Bioliver Platform and discuss it with Melanie, please come and visit the ILC in Vienna.

Please do not hesitate to contact Melanie Krüger if you require any further information:

Biochemical Engineer
Melanie Krüger
Call at +31 40 298 93 93 or e-mail us

Relevant links and background information:

  • * The BIOGEL Marie Skłodowska-Curie Innovative Training Networks (ITN-ETN) is a major European research and training consortium in the framework of H2020 programme. [ Case description: link]  

 

  • ** Dr. Bart Spee is one of the speakers: [ program ]  

 

  • BioLiver Platform service description (including downloadable factsheet PDF): [ link ]

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