The Cardiac BioSimulator
LifeTec Group’s Cardiac BioSimulator platforms are extremely suitable for visualization studies and training sessions.
The fluid circulation to which the cadaveric heart is connected consists of a preload system that provides venous pressure to the atrium, and a Windkessel afterload system allows to tune the arterial pressures. In contrast to PhysioHeart where the heart itself is the pump, in the Cardiac Biosimulator platform an external pump actuates the heart. A computer controlled stroke volume is provided to the ventricle via a cannule, thus generating the cardiac output of the model.
Vascular add-ons can provide relevant access pathways into the heart to simulate device delivery. Our team has extensive experience in direct trans-apical, trans-aortic, venous and transseptal delivery methods for cardiac devices.

R&D for device innovation
Visualizing the device delivery and deployment of your cardiovascular device in a pressurized heart with realistic hydrodynamics, heart wall movement and heart valve opening and closing behavior allows you to closely assess the functionality, implantability, and operability of your device. This makes the Cardiac BioSimulator a great tool in the early R&D phase for new devices
Lease of BioSimulation Technologies
Using our lab for a study as a service is in most cases the first step in working with LifeTec Group. A lease is often the next step in using our simulators, after having been familiarized during one or more experiments at our lab. A lease agreement can run from a minimum of 3 months and allows you to use the system at your own lab whenever you need it.
Prior to receiving the system, we will train one or more people of your staff in the best way to use the system for your specific situation. This is most useful to quickly drive development of a device, as it allows for minimal delay between updating a prototype and testing it. On top of that, this can be the best way to support training activities, as it allows for great flexibility in planning training sessions, which can often be a bottleneck in the clinical field.
Imaging compatibility
The Cardiac BioSimulator provides great imaging opportunities. With direct endoscopic video the platform allows very intuitive real-time images from inside the heart. This clearly shows the positioning of a device and the interaction with the internal cardiac tissue structures. Video offers a great detail of visual feedback, for studying prototype devices as well as instructing new clinical users on the individual procedural steps that are required during an intervention.
The platform is also compatible with clinical imaging modalities. 3D ultrasound is available in-house and the BioSimulator platform is adjusted for fluoroscopy, CT or MRI imaging in external facilities. This provides a perfect combination of visualization possibilities from which to study and learn!

Download the Factsheet
Interested in more information on the Cardiac BioSimulator? Please download our brochure!